The DermoElectroPoration® System is a Class II FDA cleared biophysical alternative to infuse high weight molecule modalities into the dermis without the use of needles!  DEP Medical is the exclusive North American distributor of  Transderm® Infusion.

No Needles

No Pain

No Downtime!

DermoElectroPoration® (DEP) is a patented, proprietary technology from Mattioli Engineering. It utilizes the skins water based “channels” to allow ionic drug solutions to penetrate due to controlled “electroporation-like” continuous reversed polarity electrical pulses. Because of this, DermoElectroPoration® is able to control the average pulse value and vary the pulse shape according to the skin’s specific electrical impedance.

DermoElectroPoration® promotes the transdermal delivery of both micro- and macro molecules (up to 2 million Dalton weight) safely into the body without the need of modifying the ionic drug solution pH, as with traditional iontophoresis. DermoElectroPoration® does not require a pH compensation patch, driving gels, or pre-charged ions.

Unlike traditional iontophoresis, DermoElectroPoration® does not have an electrolysis reaction at the site of the electrodes. There is no degradation of the molecule being delivered. This means that both positive and negative ions of the drug are delivered into the body – the drug is delivered as a whole.

DermoElectroPoration® is the only transdermal delivery device FDA cleared for the local administration of ionic drug solutions into the body for medical purposes and can be used as an alternative to injections.

DEP (DermoElectroPoration®) System is the new non-invasive, stand alone powered drug-delivery system.

DermoElectroPoration® increases the skin’s permeability by using the skin’s water based channels opened by a particular controlled current delivered to the patient, therefore allowing the substances to be absorbed by the hypodermis and muscle membranes.

Perfect for Med-Spas Dermatologists Nurse Practitioners Plastic Surgeons

The Benefits to You and Your Patients

Enhance your current cosmetic procedures.

No Anesthetic required.
Gain the ability to infuse a wide variety of modalities into different layers of the skin and Sub-Q for maximum efficacy.

No erythema. No edema. No risk of infection.

Video courtesy of Scott Callahan, PA-C.